Modern Probe-Assisted Methods for the Specific Detection of Bacteria

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This review intends to present an overview of methods currently under development for the specific and sensitive detection of pathogenic bacteria that exist in a variety of human environments. Bacteria continue to be a major health threat in general, and much effort is being deployed to counteract this problem. In a first instance, current and efficient techniques in use for the detection of bacteria are described. In a second instance, this review serves to compare the more conventional techniques to emerging technologies for the direct (non-labelled) detection of bacteria (referred to as “biosensors”). These approaches are mainly optical, piezoelectric, and electro-chemical in nature. They are cost-effective, quite sensitive, and potentially portable for rapid on-site/real-time detection, and rapid prevention. These devices are comprised of specific chemical/ biochemical probes immobilized onto physical transducers. This work also presents comparisons between the efficiencies (assay time and sensitivity) of various techniques being employed.

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Shabani, A. , Marquette, C. , Mandeville, R. and Lawrence, M. (2015) Modern Probe-Assisted Methods for the Specific Detection of Bacteria. Journal of Biomedical Science and Engineering, 8, 104-121. doi: 10.4236/jbise.2015.82011.


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