Management of a Severe Form of Verneuil’s Disease in Its Genitoperineal Localisation in Bobo-Dioulasso

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The authors report a severe form of genitoperineal localisation of Verneuil’s disease managed in a surgical environment, having evolved favorably with improvement of the patient’s quality of life, but persistence of unsightly skin scars. They insist on the unexceptional nature of this disease whose prognosis is reserved, sometimes leaving severe functional sequelae. The long evolution of the disease with prolonged hospitalization in a professionally active young patient and the extension of suppurations to the perineal, scrotal and inguinal regions was the features of this observation. After wide excision of the lesions with antibiotic associated with local care, evolution had taken to complete wound healing with improved quality of life and a recovery of his professional activity.

Cite this paper

Cyprien, Z. , Adama, O. , Timothée, K. , Edgar, O. , Boukary, D. , Ibrahim, T. , Drissa, B. , Bakary, S. , Delphine, Y. and Simon, T. (2015) Management of a Severe Form of Verneuil’s Disease in Its Genitoperineal Localisation in Bobo-Dioulasso. Open Journal of Urology, 5, 13-18. doi: 10.4236/oju.2015.52003.

References

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[10] Tamant, J.C., Bruant-Rodier, C., Nunziata, J.F. and Wilk, A. (2013) Dégénérescence de maladie de Verneuil en carcinome épidermoide: à propos de 2 cas et revue de la littérature. Annales de chirurgie plastique esthetique, 51, 82-86.                                                                                       eww150212lx
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Colorectal Cancer Surgery in Extreme Elderly Population

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=52682#.VKC8gcCAM4

Author(s)

Javier Gallego Plazas1*, Elena Asensio1, Juan C. Navalon2, Inmaculada Lozano1, Jose M. Navarro2, Guillermo Ricote1, Montse Olcina2, Almudena Cotes1, Henry M. Ore1, Alejandra Magdaleno1, Maria C. Ors1, Maria J. Escudero1, Miguel A. Morcillo2

Affiliation(s)

1Servicio de Oncología Médica, Hospital General Universitario de Elche-Hospital Vega Baja, Alicante, Espana.
2Servicio de Cirugía General, Hospital Vega Baja, Alicante, Espana.

ABSTRACT

Background: Colorectal cancer surgery in extreme elderly population (380 years) is a growing problem and a subject in question. Experiences and results in this scenario are limited. Methods: Medical records of patients 380 years old hospitalized in General Surgery Department in Vega Baja Hospital between January 1st 2008 and December 31st 2012 were retrospectively reviewed. Patients diagnosed with colorectal cancer (CRC) were selected. Data regarding comorbidities, treatment performed, complications and survival were collected. Results: 95 patients (74 colon, 21 rectum) were identified: median age 83.0 years (80 – 93), 64.2% males. 93.7% of patients were operated on: median hospital and post-operative stay of 11 and 9 days, respectively; curative intention surgery 82.1%. 4.2% of patients were treated with interventionist procedures, and 2.1% of patients in a conservative way. 17.9% and 4.2% of patients came up with early and late complications, respectively. Early and late mortality occurred in 9.5% and 3.2% of patients, respectively. By March 2014, with a median follow up of 43.8 months, median overall survival for colorectal cancer patients was 2.7 years (95%IC, 2.0 – 3.2). Univariaye Cox Regresion analysis revealed the presence of cardiomyopathy (p = 0.024), the presence of chornic kidney disease (p = 0.025), the presence of comorbidities (vs absence) (0.026), the number of comorbidities (0.034), type of admission (p = 0.001), treatment with surgery (p = 0.001) and the incidence of early (p = 0.004) or late complications (p = 0.023) associated to overall survival with statically significance. Multivariate Cox Regression analysis showed number of comorbidities (HR = 1.104; 95%CI: 0.851 – 1.431; p = 0.456), treatment with surgery (HR = 4.928; 95%CI: 1.815 – 13.385; p = 0.002), programmed admission into hospital (HR = 2.316; 95%CI: 1.298 – 4.133; p = 0.004), and the incidence of late complications (HR = 4.629; 95%CI: 1.279 – 16.750; p = 0.020) independently associated with overall survival. Interaction test between number of comorbidities and early complication was performed (HR = 1.453; 95%CI: 0.971 – 2.175; p = 0.070). Conclusions: In our experience surgery for CRC patients may increase overall survival even in an extreme elderly population (380 years). Nevertheless when considering surgery for CRC in this subgroup of patients, factor such as type of admission into hospital and comorbidities should be taken into account in order to optimize treatment results in the effort to individualize CRC management in this growing population.

KEYWORDS

Colorectal, Cancer, Surgery, Elderly

Cite this paper

Plazas, J. , Asensio, E. , Navalon, J. , Lozano, I. , Navarro, J. , Ricote, G. , Olcina, M. , Cotes, A. , Ore, H. , Magdaleno, A. , Ors, M. , Escudero, M. and Morcillo, M. (2015) Colorectal Cancer Surgery in Extreme Elderly Population. Journal of Cancer Therapy, 6, 12-20. doi: 10.4236/jct.2015.61002.

References

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Rate of Recurrence of Non-Small Cell Lung Cancer in Patients Treated with Percutaneous Ablation

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=51369#.VGVZIGfHRK0

ABSTRACT

Background: Percutaneous ablation therapy as a treatment for non-small cell lung cancer (NSCLC) has been increasingly utilized. There is little data on long term efficacy. Because of this we reviewed the rate of recurrence of all ablation procedures done at our institution for the last 6 years. Methods: A total of 36 patients underwent 43 percutaneous procedures from July 2008 until January 2014 at our institution. There were 9 patients treated with radiofrequency ablation (RFA) and 27 treated withmicrowave ablation (MWA) for Stage I NSCLC. Each patient was reviewed to determine if there was a recurrence, the time to recurrence and the characteristics of the original cancer possibly predisposing the procedure to failure. Results: There were 8 recurrences in 9 patients undergoing RFA occurring at a median time of 842 days (range 425 – 1568) after their procedure. MWA was utilized in 27 patients for 34 procedures with 11 patients experiencing recurrences at a median time of 487 days (range 168 – 845). The median follow up time for the RFA patients was 1631 days (4.46 years) and for the MWA patients 751 days (2.06 years). Of the RFA recurrences, 5 involved systemic spread of their cancer and 3 were limited to site recurrences only. Of the MWA recurrences, 5 involved systemic spread of their cancer, 2 had chest wall recurrences and 4 were limited to site recurrences only.

Cite this paper

S. Regmi, N. , Heber, B. and W. Klena, J. (2014) Rate of Recurrence of Non-Small Cell Lung Cancer in Patients Treated with Percutaneous Ablation. Advances in Lung Cancer, 3, 75-81. doi: 10.4236/alc.2014.34011.

References

[1] Alexander, E.S. and Dupuy, D.E. (2013) Lung Cancer Ablation: Technologies and Techniques. Seminars in Interventional Radiology, 30, 141-150. http://dx.doi.org/10.1055/s-0033-1342955
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Congenital Granular Cell Lesion: A Case Report

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50796#.VE8L3lfHRK0

ABSTRACT

The congenital granular cell lesion is a rare disease that affects newborns. We present a case of a patient with nodular lesions that were located on the anterior part of the maxillary alveolar. The surgical resection of the one lesion and its histological and immunohistochemical study were made.

Cite this paper

Paulo, D. , Barbosa, B. , Ibiapina, J. , Rebelo, A. , Carvalho, T. and Santos, L. (2014) Congenital Granular Cell Lesion: A Case Report. Case Reports in Clinical Medicine, 3, 566-569. doi: 10.4236/crcm.2014.310123.

References

[1] Azevedo, R.A., Galli, G.B., Pereira, C.L. and Pires, M.S.M. (2005) Epúlide Congênita. RGO, Porto Alegre, 53, 206-209.
[2] Chami, R.G. and Wang, H.S. (1986) Large Congenital Epulis of Newborn. Journal of Pediatric Surgery, 21, 929-930. http://dx.doi.org/10.1016/S0022-3468(86)80091-4
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[5] Yavuzer, R., Ataoglu, O. and Sari, A. (2001) Multiple Congenital Epulis of the Alveolar Ridge and Tongue. Annals of Plastic Surgery, 47, 199-202.
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[8] Silva, G.C.C., Vieira, T.C., Vieira, J.C., Martins, C.R. and Silva, E.C. (2007) Congenital Granular Cell Tumor (Congenital Epulis): A Lesion of Multidisciplinary Interest. Medicina Oral Patologia Oral y Cirugia Bucal, 12, 428-430.
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[10] Lopez-Lacalle, J.M., Aguirre, I., Irizabal, J.C. and Nogues, A. (2001) Congenital Epulis: Prenatal Diagnosis by Ultrasound. Pediatric Radiology, 31, 453-454.
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http://dx.doi.org/10.1097/00005537-200211000-00005                                                  eww141028lx

Congenital Granular Cell Lesion: A Case Report

Read  full  paper  at:

http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50796#.VE3cP1fHRK0

ABSTRACT

The congenital granular cell lesion is a rare disease that affects newborns. We present a case of a patient with nodular lesions that were located on the anterior part of the maxillary alveolar. The surgical resection of the one lesion and its histological and immunohistochemical study were made.

Cite this paper

Paulo, D. , Barbosa, B. , Ibiapina, J. , Rebelo, A. , Carvalho, T. and Santos, L. (2014) Congenital Granular Cell Lesion: A Case Report. Case Reports in Clinical Medicine, 3, 566-569. doi: 10.4236/crcm.2014.310123.

References

[1] Azevedo, R.A., Galli, G.B., Pereira, C.L. and Pires, M.S.M. (2005) Epúlide Congênita. RGO, Porto Alegre, 53, 206-209.
[2] Chami, R.G. and Wang, H.S. (1986) Large Congenital Epulis of Newborn. Journal of Pediatric Surgery, 21, 929-930. http://dx.doi.org/10.1016/S0022-3468(86)80091-4
[3] Menéndy, O.R. (1989) Estomatologia Pediátrica. In: Tommasi, A.F., Ed., Diagnóstico em Patologia Bucal, Vol. 2, Pancast Editorial, São Paulo, 559-586.
[4] McGuire, T.P., Gomes, P.P., Freilich, M.M. and Sándor, G.K. (2006) Congenital Epulis: A Surprise in the Neonate. Journal of the Canadian Dental Association, 72, 747-750.
[5] Yavuzer, R., Ataoglu, O. and Sari, A. (2001) Multiple Congenital Epulis of the Alveolar Ridge and Tongue. Annals of Plastic Surgery, 47, 199-202.
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http://dx.doi.org/10.1097/00005537-200211000-00005                                                             eww141027lx

The Palmar Cutaneous Branch of the Median Nerve: A Detailed Morphometric Study

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50821#.VE2ZIFfHRK0

ABSTRACT

Damage to the palmar cutaneous branch of the median nerve (PCBMN) is a potential complication of surgery at the volar aspect of the wrist. The aim of this study was to determine the relationships of the PCBMN to both surface and bony landmarks using reliable methods. Ten pairs of forearms from cadavers aged 73 to 98 years were dissected. The PCBMN was identified and its course and relationships documented. The situation of the PCBMN was quantified relative to the distal wrist crease, bistyloid line, scaphoid tubercle, radial styloid process and flexor carpi radialis tendon. A PCBMN was identified on 90% of sides. The PCBMN arose from the radial aspect of the median nerve 52.4 (SD 31.0) mm from the bistyloid line and entered the transverse carpal ligament 10.9 (SD 9.5) mm proximal to the bistyloid line. At the level of the distal wrist crease the PCBMN was located 0.6 to 7.5 mm (mean 4.5; SD 1.9 mm) from the ulnar aspect of the flexor carpi radialis tendon. The inter- and intra-observer reliability of the measurement methods ranged from ICC 0.96 to 1.00. Detailed morphometric data of the PCBMN relative to bony landmarks contribute to knowledge of the spatial relationships of the PCBMN to inform the precision of surgical incisions.

Cite this paper

Richards, O. , Border, S. , Bolton, C. and Webb, A. (2014) The Palmar Cutaneous Branch of the Median Nerve: A Detailed Morphometric Study. Forensic Medicine and Anatomy Research, 2, 101-106. doi: 10.4236/fmar.2014.24017.

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Embryonal Rhabdomyosarcoma of the Uterine Cervix: Two Cases Report and Literature Review

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http://www.scirp.org/journal/PaperInformation.aspx?PaperID=50622#.VEcHqFfHRK0

ABSTRACT

Introduction: Embryonal rhabdomyosarcoma (RMS) of the uterine cervix is a rare and extremely aggressive malignant entity. However, prognosis seems to be improved with the use of multimodality approach treatment. Cases: We report the cases of 50- and 51-year-old women, presenting with vaginal bleeding and mass. The two patients underwent radical surgery. Histological examination revealed RMS of uterine cervix. Treatment was effective in the first case but despite the chemotherapy, the second patient died two months later. Discussion and Conclusions: The prognosis of the cervical embryonal RMS depends on clinical and histological features. The current treatment protocols are based on trials done on pediatric patients. Studies on embryonal RMS treatment and outcomes are limited in women over forty years. In patients with unfavorable prognosis characteristics, the multimodality approach including surgery, adjuvant chemo and radiotherapy can be effective. Otherwise, surgery alone can effectively be proposed.

Cite this paper

Abdeljalil, K. , Asma, B. , Kouira, M. , Faten, H. , Sawssen, M. , Samir, H. , Mohamed, B. , Habib, E. and Hedi, K. (2014) Embryonal Rhabdomyosarcoma of the Uterine Cervix: Two Cases Report and Literature Review. Open Journal of Obstetrics and Gynecology, 4, 868-873. doi: 10.4236/ojog.2014.414122.

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